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Arch Dis Child ; 107(2): 186-188, 2022 02.
Article in English | MEDLINE | ID: covidwho-1322772

ABSTRACT

BACKGROUND: Children with cancer are not at increased risk of severe SARS-CoV-2 infection; however, adults with haematological malignancies have increased risk of severe infections compared with non-haematological malignancies. METHODS: We compared patients with haematological and non-haematological malignancies enrolled in the UK Paediatric Coronavirus Cancer Monitoring Project between 12 March 2020 and 16 February 2021. Children who received stem cell transplantation were excluded. RESULTS: Only 2/62 patients with haematological malignancy had severe/critical infections, with an OR of 0.5 for patients with haematological compared with non-haematological malignancies. INTERPRETATION: Children with haematological malignancies are at no greater risk of severe SARS-CoV-2 infection than those with non-haematological malignancies.


Subject(s)
COVID-19/epidemiology , Hematologic Neoplasms/epidemiology , Severity of Illness Index , Adolescent , COVID-19/diagnosis , COVID-19/immunology , COVID-19/virology , Child , Child, Preschool , Cohort Studies , Female , Hematologic Neoplasms/immunology , Humans , Infant , Male , Risk Assessment/statistics & numerical data , Risk Factors , SARS-CoV-2/immunology
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